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The following has been copied from the ACC website:

Expect a dog you can take everywhere, one that has little or no shedding, little or no dander (a cause of allergies in people), little or no doggy odor, a dry hairlike coat that
sheds dirt, a dog clean enough to sleep in your bed, and a dog that has no significant genetic disease built into the breed.  a dry hairlike coat that sheds dirt, a dog clean
enough to sleep in your bed, and a dog that has no significant genetic disease built into the breed.  a dry hairlike coat that sheds dirt, a dog clean enough to sleep in your
bed, and a dog that has no significant genetic disease built into the breed.  The Coton de Tulear is still remarkably free of genetic disease.  There are perhaps 45-55
known genetic diseases in Cotons (compared to hundreds in The Coton de Tulear is still remarkably free of genetic disease.  There are perhaps 45-55 known genetic
diseases in Cotons (compared to hundreds in other more common breeds).  The known incidence of any particular genetic problem is low, in the 1-5% range.  Often in
other breeds, the incidence of one or more diseases can be greater than 50% in the population and presents a real problem to long term breed vitality.  The known
incidence of any particular genetic problem is still quite low.  It is good to be aware of possible health problems but health information which appears on this web site is not
meant to convey that there is a particular health problem in the breed.  You can learn here about eye health,  a recently discovered blood disorder, von Willebrands
Disease which is common in some breeds but still rare in Cotons, Progressive Retinal Atrophy (
PRA), which is still rare in Cotons, and a variety of problems reported by
Coton owners in the Coton Community Health Survey.  ACC breeders maintain a lifelong educational commitment to learning as much about the breed as possible.  It's
always a good idea to ask the breeders you approach for puppies if they health test their dogs and what they can tell you about any potential problems in their lines.   
Although "bad" dogs can come from good breeders, you should expect a healthy, long lived Coton if you carefully select your breeder. Other sources of information are:
The talking Heads
Bandera's syndrome
ACC health survey
G&P on Coton Health
Puppymill Hell